Abstract
An experiment was conducted to study the haemato-biochemical alterations induced by Gamma-Hexachlorocyclohexane (γ-HCH) in 72 male Wistar rats, divided uniformly into four different groups for a period of 45 days. Rats of group I received only water as control, group II rats received orally 20mg/kg body wt of γ-HCH and group III rats gavaged by 100mg/kg body wt of Camellia sinensis (green tea) while group IV rats received both γ-HCH and green tea. Blood and serum were collected on 15th, 30th, 45th day of experiment. Group II rats showed significant reduction in total erythrocyte count, packed cell volume and non-significant reduction in total leukocyte count compared to control. There was significant rise in values of serum creatinine, alkaline phosphatase (ALP) and aspartate aminotransferase (AST). The results showed that Camellia sinensis could have alleviating effect on the toxicity caused by γ-HCH in rats.
Published Version
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