Abstract
A patch of layer 1 inhibitory interneurons from turtle visual cortex was modeled in order to explore the functional roles of inhibitory interactions between inhibitory interneurons. A simulated light flash produced action potentials in the neurons with latencies of 37–52ms. Blocking GABAA receptor-mediated inhibition resulted in doublets of action potentials in many cells and increased the range of spike latencies to 37–69ms. Inhibitory interactions between inhibitory cells may serve to produce a strong and temporally focused inhibition of pyramidal cells and to regulate the occurrence of spike doublets that are thought to be important in generating synchronous oscillations in cortex.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
