Functional assessment of microcirculation in the injection site tissues when using local anaesthesia

Abstract

Relevance. In modern dentistry, the primary criteria for successful anaesthesia are the effectiveness and safety of the anaesthetic used. These factors depend on the type of local anaesthetic and the method of its administration in the maxillofacial tissues. Studying the impact of locally anaesthetizing solutions administered by different injection techniques on the periodontal tissues is possible by recording changes in microcirculation using the LDF method.Purpose. To dynamically record the baseline microcirculation indicator in the tissues at the injection site when using various methods and means of local anaesthesia.Materials and methods. The study of changes in the microcirculation of periodontal tissues was conducted among 105 patients: 67 women and 38 men aged 25 to 56 years without periodontal pathology and comorbidities, using injection methods of anaesthesia (infiltration and modified periodontal anaesthesia) with 2% and 4% solutions of articaine with varying concentrations of vasoconstrictor. Changes in the microcirculation index were recorded at the injection site: at the root apex projection during infiltration and in the gingival papilla region during MPA, with an exposure time during LDF registration of 5 minutes. To maintain the fiber optic probe, an individual key made of C-silicone with an additional corrective layer was used for repeat positioning. The most informative indicator of the study was the magnitude of the average blood perfusion flow (M) in the time interval of registration, with its changes reflected in the study results.Results. Analysis of the dynamics of microcirculation indicators in the injection site tissues when using various methods of administering locally anaesthetizing drugs based on 2% and 4% solutions of articaine without vasoconstrictor and with epinephrine at concentrations of 1:200,000 and 1:100,000 allowed the determination of tissue ischemia depth at the injection site and the rate of blood flow restoration after anaesthesia.Conclusion. Changes in microcirculation indicators in the tissues at the injection site of the local anaesthetic depend on the concentration of the local anaesthetic and vasoconstrictor, the method of administration used, and the volume of the drug administered.