Abstract
Techniques to analyze diffusion tensor MRI (DT-MRI) datasets in the myocardium are limited. In a recent major advance, diffusion MRI tractography was used to visualize myofiber bundles as continuous 3-dimensional tracts (Circ Cardiovasc Imaging. 2009; 2(3):206-12). However, the tractographic scheme used in this work, while of major value, was purely qualitative. A strong need exists to develop quantitative tools for the visualization and analysis of diffusion MRI tractography datasets in the heart.
Highlights
Techniques to analyze diffusion tensor MRI (DT-MRI) datasets in the myocardium are limited
The normalized quadratic error (NQE) was defined by the quadratic error between these helix angle profiles summed across the myocardium (Figure 1D)
NQE values were < 5 when tract length was limited to 50% of the ventricular circumference
Summary
From qualitative to quantitative tractography: a novel method to measure variation and error in diffusion mr tractography datasets of the myocardium. Choukri Mekkaoui1*, Shuning Huang, Guangping Dai, Timothy G Reese, Aravinda Thiagalingham, Udo Hoffmann, Marcel P Jackowski, David E Sosnovik. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011
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