Abstract
Tuberculous Lymphadenitis (TBLA) poses a significant public health burden globally, particularly in Somalia due to high tuberculosis prevalence. It often faces diagnostic challenges due to its nonspecific symptoms; making early treatment critical. Additionally, high HIV and MDR-TB burden can also exacerbate the scenario. Hence, this study aims to determine the rate of TBLA in Somali population using GeneXpert PCR assay. This retrospective observational study was conducted at NOVA Diagnostic and Research, a leading diagnostic center in Mogadishu, Somalia, from January 2024 to August 2024. A total of 499 suspected cases were included. Among the study participants, the male-to-female ratio was 0.98:1. 36.07% of individuals tested positive for TBLA. The disease was found to be more prevalent among younger participants, particularly those under the age of 40. A significant association was observed between the site of aspiration and TB positivity (p<0.005), with cervical lymph nodes being the most commonly affected site, accounting for 67.2% of positive cases. Additionally, TB was detected in multiple lymph node sites in 8.3% of the all specimens. In Somalia, the rate of TBLA continues to remain elevated, especially in younger population. More strategic approach is necessary to reduce the burden effectively. Rapid and accurate diagnosis of TBLA can be performed by GeneXpert real-time PCR, for early detection and treatment.
Published Version
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