Abstract
Objective: To know the prevalence of congenital anomalies in foeti on antenatal ultrasonography and role of preconceptual folic acid intake in preventing development of neural tube defects. Study Design: Cross-sectional Descriptive study. Setting: Department of Pediatric Surgery, Mayo Hospital, Lahore. Period: January 2022 to September 2022. Material & Methods: The data of 57 patients was collected, who were referred to Pediatric Surgery Department of Mayo Hospital, Lahore from lady Wallington Hospital and Lady Aitchison Hospital, with fetal anomaly detected on antenatal scan. Women with pregnancy in second and third trimester, ranging in age from 20 to 45 years, were enrolled in the study. A questionnaire was used to collect the data. We analyzed the data of study usingSPSS 20(Statistical Package for Social Sciences version 20). Results: Data analysis showed higher incidence (34%) of anomalies of central nervous system including neural tube defects. 89% (51/57) women had not taken preconceptual folic acid supplements. Consanguinity was also noted to be an important factor and significant correlation was seen 70% (40/57). Conclusion: The incidence of central nervous system anomalies including neural tube defects was higher (34%) among all anomalies. This might be probably due to preconceptual deficiency of folic acid.
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