Abstract
Conventional dosage forms frequently produce leakages and drip. There is a need for the development of innovative formulation technology that fulfills certain criteria such as desirable product dispersion throughout the system, retention for intended intervals, and adequate release of drug. These features can be achieved using bioadhesives based novel delivery systems. In-situ gelation is a process of gel formation at the site of application after the composition or formulation has been applied the site. Formulation and evaluation of one such bioadhesive based novel drug delivery system for an effective and patient friendly use of drug to formulated In-situ polyherbal gel. Piper betel L. (Pan, leaves) fam. Piperaceae; Spilanthesacmella Murr. (Akarkara, fruit), fam. Asteraceae; Foeniculum vulgare Mill. (Fennel, fruits) fam. (Umbelliferae); Eugenia caryophyllus (Spreng.) Bullock and S.G. Harrison (Clove, clove bud) fam. (Myrataceae) and Capsicum annum L. (Capsicum, fruits) fam. Solanaceae is medicinally important and is used as local anesthetics in oral cavity and these herbs were taken for formulation of polyherbal gel using Carbopol 934 and HPMC. The prepared formulation was evaluated, and the results were presented. The results indicate that the PHG-3 have satisfactory results when compared with other formulated PHG.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
