Food Safety Objective: An Integral Part of Food Chain Modelling
The supply and maintenance of safe and wholesome foods to a population is a complex system involving mul- tiple stakeholders. An organizational scheme for representing this complexity is a food chain. A food chain also provides the appropriate structure for the management and communication of food risks. A natural extension of this framework is the concept of a food safety objective. The mathematical form of the food safety objective is a mathematical inequality which consistently incorporates a mechanism for combining objective and subjective risk in a single framework. Addi- tionally, the food safety objective mathematical inequality can be adapted to include uncertainty, when information is im- precise or unknown. This extension involves the use of statistical distribution to represent quantitative terms in the expres- sion. Food chain modeling using the FSO framework provides a useful tool for managing the complexity inherent in the supply of safe foods.
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The current status of the food safety supply world wide, has led Food and Agriculture Organization (FAO) and World Health Organization (WHO) to establishing Risk Analysis as the single framework for building food safety control programs. A series of guidelines and reports that detail out the various steps in Risk Analysis, namely Risk Management, Risk Assessment and Risk Communication is available. The Risk Analysis approach enables integration between operational food management systems, such as Hazard Analysis Critical Control Points, public health and governmental decisions. To do that, a series of new Risk Metrics has been established as follows: i) the Appropriate Level of Protection (ALOP), which indicates the maximum numbers of illnesses in a population per annum, defined by quantitative risk assessments, and used to establish; ii) Food Safety Objective (FSO), which sets the maximum frequency and/or concentration of a hazard in a food at the time of consumption that provides or contributes to the ALOP. Given that ALOP is rather a metric of the public health tolerable burden (it addresses the total ‘failure’ that may be handled at a national level), it is difficult to be interpreted into control measures applied at the manufacturing level. Thus, a series of specific objectives and criteria for performance of individual processes and products have been established, all of them assisting in the achievement of FSO and hence, ALOP. In order to achieve FSO, tools quantifying the effect of processes and intrinsic properties of foods on survival and growth of pathogens are essential. In this context, predictive microbiology and risk assessment have offered an important assistance to Food Safety Management. Predictive modelling is the basis of exposure assessment and the development of stochastic and kinetic models, which are also available in the form of Web-based applications, e.g., COMBASE and Microbial Responses Viewer), or introduced into user-friendly softwares, (e.g., Seafood Spoilage Predictor) have evolved the use of information systems in the food safety management. Such tools are updateable with new food-pathogen specific models containing cardinal parameters and multiple dependent variables, including plate counts, concentration of metabolic products, or even expression levels of certain genes. Then, these tools may further serve as decision-support tools which may assist in product logistics, based on their scientifically-based and “momentary” expressed spoilage and safety level.
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29
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38
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The World Trade Organization introduced the concept of appropriate level of protection (ALOP) as a public health target. For this public health objective to be interpretable by the actors in the food chain, the concept of food safety objective (FSO) was proposed by the International Commission on Microbiological Specifications for Foods and adopted later by the Codex Alimentarius Food Hygiene Committee. The way to translate an ALOP into a FSO is still in debate. The purpose of this article is to develop a methodological tool to derive a FSO from an ALOP being expressed as a maximal annual marginal risk. We explore the different models relating the annual marginal risk to the parameters of the FSO depending on whether the variability in the survival probability and in the concentration of the pathogen are considered or not. If they are not, determination of the FSO is straightforward. If they are, we propose to use stochastic Monte Carlo simulation models and logistic discriminant analysis in order to determine which sets of parameters are compatible with the ALOP. The logistic discriminant function was chosen such that the kappa coefficient is maximized. We illustrate this method by the example of the risks of listeriosis and salmonellosis in one type of soft cheese. We conclude that the definition of the FSO should integrate three dimensions: the prevalence of contamination, the average concentration per contaminated typical serving, and the dispersion of the concentration among those servings.
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7
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- Oct 29, 2013
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Microbiological food safety is an important economic and health issue in the context of globalization and presents food business operators with new challenges in providing safe foods. The hazard analysis and critical control point approach involve identifying the main steps in food processing and the physical and chemical parameters that have an impact on the safety of foods. In the risk-based approach, as defined in the Codex Alimentarius, controlling these parameters in such a way that the final products meet a food safety objective (FSO), fixed by the competent authorities, is a big challenge and of great interest to the food business operators. Process risk models, issued from the quantitative microbiological risk assessment framework, provide useful tools in this respect. We propose a methodology, called multivariate factor mapping (MFM), for establishing a link between process parameters and compliance with a FSO. For a stochastic and dynamic process risk model of Listeriamonocytogenes in soft cheese made from pasteurized milk with many uncertain inputs, multivariate sensitivity analysis and MFM are combined to (i) identify the critical control points (CCPs) for L.monocytogenes throughout the food chain and (ii) compute the critical limits of the most influential process parameters, located at the CCPs, with regard to the specific process implemented in the model. Due to certain forms of interaction among parameters, the results show some new possibilities for the management of microbiological hazards when a FSO is specified.
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5
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