Abstract
Background: Syzygium cumini L., commonly known as Jamun, black-plum, and Indian blackberry, is one of the most widely distributed trees in India with booming medical benefits and possesses antioxidant, anticancer and anti-diabetic properties. It belongs to the family Myrtaceae. Despite countless phytochemicals, seeds are not consumed and are the waste part of Jamun fruit. Objective: The objective of this study was to evaluate the antioxidant capacity of phenolics from Jamun seeds against a bundle of oxidant moieties. Methods: The 50% acetone extract of Jamun seeds was investigated for in-vitro antioxidant profiling. Assays include free radical scavenging activity, metal chelation activity, hydroxyl radical scavenging activity, hydrogen peroxide scavenging activity, total antioxidant activity, total reducing power, nitric oxide scavenging activity, and lipid peroxidation inhibition activity. Results: The extract depicted maximum DPPH radical scavenging activity followed by ABTS radical scavenging activity. Hefty metal chelation and nitric oxide scavenging activity were recorded while lipid peroxidation, H2O2, and OH- scavenging activity was intermediate. Conclusion: Jamun seed showed ample antioxidant activity and certifies that it is the right candidate for exploitation as a source of natural antioxidants to counteract autoxidation-induced pathologies or diseases.
Highlights
The cellular level of Reactive Oxygen Species (ROS) is regulated by the interaction of complex antioxidant types of machinery in living systems
The extract depicted maximum DPPH radical scavenging activity followed by ABTS radical scavenging activity
Jamun seed showed ample antioxidant activity and certifies that it is the right candidate for exploitation as a source of natural antioxidants to counteract autoxidation-induced pathologies or diseases
Summary
The cellular level of Reactive Oxygen Species (ROS) is regulated by the interaction of complex antioxidant types of machinery in living systems These natural antioxidants are well known to curtail the adverse effects of free radicals and withstand oxidative damage in biological entities. Fat, glycosides, jambosine, resin, ellagic acid, quercetin, gallic acid, as well as elements such as zinc, vanadium, sodium, and potassium [8] Despite these phytochemicals, seeds are not consumed and are the waste part of Jamun fruit. Syzygium cumini L., commonly known as Jamun, black-plum, and Indian blackberry, is one of the most widely distributed trees in India with booming medical benefits and possesses antioxidant, anticancer and anti-diabetic properties. Seeds are not consumed and are the waste part of Jamun fruit
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