Abstract
The distribution of lipids of Propionibacterium acnes (Corynebacterium parvum) vaccine strain in chloroform-methanol, ethanol and light petroleum extracts was determined. Firmly bound lipids released by hydrolysis were also investigated. The petroleum extract differs from other lipidic fractions in its fatty acid composition. The presence of linolic, tuberculostearic and 10-ketostearic acids and branched fatty alcohols was observed in addition to previously described fatty acids of P. acnes. Changes in fatty acid composition during growth of the vaccine strain were determined and extremes were found at 95 h of cultivation. These extremes coincided with a maximum in the immunostimulatory efficiency as measured by the spleen enlargement test. The biological activity of static and stirred cultures of the vaccine strain was in correlation with their fatty acid composition.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
