Facile synthesis of hypercrosslinked polymer as high-efficiency adsorbent for the enrichment of nitroimidazoles from water, honey and chicken meat

Abstract

Design and fabrication of functionalized hypercrosslinked polymers (HCPs) for enhancing their performance by using green renewable monomers has attracted considerable research interest. In this study, hydroxyl‑functional HCP (labeled as OHHCP) was prepared via the knitting method by applying natural naringenin as a monomer for the first time. Due to the good hydrophilicity and strong H-bonding ability, the OHHCP showed high extraction capacity for nitroimidazoles. Thus, it was successfully applied as a potent adsorbent for solid phase extraction of five nitroimidazoles in water, honey and chicken meat, followed by high-performance liquid chromatography-diode array detector analysis. At the optimized conditions, the limit of detections (S/N = 3) of the proposed method for water, honey and chicken samples were 0.02 - 0.06 ng mL−1, 0.5 - 1.0 ng g−1 and 0.8 - 1.0 ng g−1, respectively. The recoveries were 80.0 - 110%, and the relative standard deviations were below 10.0%. The OHHCP also displayed good application prospects for other organic compounds with H-bonding capability. This study highlights the facile preparation of OH-functionalized HCPs from renewable and natural resources as potent adsorbents for polar compounds.