Facile Synthesis Of 1H-Indazoles Through IodobenzeneCatalyzed C–H Amination Under Mild And Metal-Free Conditions

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The transition-metal- and halogen-free synthesis of N-aryl substituted 1H-indazole and derivatives was accomplished on the basis of the iodobenzene-catalyzed intramolecular C -H amination of hydrazones under mild conditions. Reactions of hydrazones derived from ketones and hydrazines with a catalytic amount of iodobenzene in the presence of Oxone as an oxidant in trifluoroacetic acid took place to afford 1H indazoles in moderate to good yields.