Abstract
Deoxyepinephrine (DXEP) is a catecholamine derivative with pharmaceutical activity to raise blood pressure. Therefore, the control of DXEP in biological samples is very important for human health. The proposed research introduces a fast electro-analytical strategy based on CuFe2O4/ionic liquid (1-Hexyl-3-methylimidazolium Bromide (1H3MBr)) nanocomposite modified pate electrode (CuFe2O4/1H3MBr/PE) for voltammetric determination of deoxyepinephrine. For this goal, the CuFe2O4 as conductive mediator was synthesized using facile sonochemical method and characterized by XRD and FESEM methods. The CuFe2O4/1H3MBr/PE exhibited good performance for determination of DXEP in the presence of uric acid (UA) with separated potential ∼170 mV. The CuFe2O4/1H3MBr/PE was showed linearly proportional to DXEP and UA concentrations in the wide linear ranges from 0.3−300 μM and 0.7−300 μM with LOD of 0.09 μM and 0.4 μM, respectively. The CuFe2O4/1H3MBr/PE was suggested as an excellent platform for determination of DXEP and UA in real samples.
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