Exposure to Phthalate Esters

Abstract

LetterOpen AccessExposure to phthalate esters. R M David R M David Search for more papers by this author Published:1 October 2000https://doi.org/10.1289/ehp.108-a440aCited by:87AboutSectionsPDF ToolsDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InReddit FiguresReferencesRelatedDetailsCited by Huang P, Liao K, Chang J, Chan S and Lee C (2018) Characterization of phthalates exposure and risk for cosmetics and perfume sales clerks, Environmental Pollution, 10.1016/j.envpol.2017.10.079, 233, (577-587), Online publication date: 1-Feb-2018. Kim J, Lee S, Shin M, Kim K and Hong Y (2018) Risk assessment for phthalate exposures in the elderly: A repeated biomonitoring study, Science of The Total Environment, 10.1016/j.scitotenv.2017.08.019, 618, (690-696), Online publication date: 1-Mar-2018. Wang W, Leung A, Chu L and Wong M (2018) Phthalates contamination in China: Status, trends and human exposure-with an emphasis on oral intake, Environmental Pollution, 10.1016/j.envpol.2018.02.088, 238, (771-782), Online publication date: 1-Jul-2018. Varshavsky J, Morello-Frosch R, Woodruff T and Zota A (2018) Dietary sources of cumulative phthalates exposure among the U.S. general population in NHANES 2005–2014, Environment International, 10.1016/j.envint.2018.02.029, 115, (417-429), Online publication date: 1-Jun-2018. Lessmann F, Correia-Sá L, Calhau C, Domingues V, Weiss T, Brüning T and Koch H (2017) Exposure to the plasticizer di(2-ethylhexyl) terephthalate (DEHTP) in Portuguese children – Urinary metabolite levels and estimated daily intakes, Environment International, 10.1016/j.envint.2017.03.028, 104, (25-32), Online publication date: 1-Jul-2017. González-Mariño I, Rodil R, Barrio I, Cela R and Quintana J (2017) Wastewater-Based Epidemiology as a New Tool for Estimating Population Exposure to Phthalate Plasticizers, Environmental Science & Technology, 10.1021/acs.est.6b05612, 51:7, (3902-3910), Online publication date: 4-Apr-2017. Dziwiński E, Poźniak B and Lach J (2017) GC/MS and ESI/MS identification of the new generation plasticizers - cis and trans isomers of some 1,2-cyclohexane dicarboxylic acid di(n- and isononyl) esters, Polymer Testing, 10.1016/j.polymertesting.2017.07.011, 62, (319-324), Online publication date: 1-Sep-2017. Koch H, Rüther M, Schütze A, Conrad A, Pälmke C, Apel P, Brüning T and Kolossa-Gehring M (2017) Phthalate metabolites in 24-h urine samples of the German Environmental Specimen Bank (ESB) from 1988 to 2015 and a comparison with US NHANES data from 1999 to 2012, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2016.11.003, 220:2, (130-141), Online publication date: 1-Mar-2017. Moreau M, Leonard J, Phillips K, Campbell J, Pendse S, Nicolas C, Phillips M, Yoon M, Tan Y, Smith S, Pudukodu H, Isaacs K and Clewell H (2017) Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates, Chemosphere, 10.1016/j.chemosphere.2017.06.098, 184, (1194-1201), Online publication date: 1-Oct-2017. Chang J, Lee C, Pan W, Chou W, Huang H, Chiang H and Huang P (2017) Estimated Daily Intake and Cumulative Risk Assessment of Phthalates in the General Taiwanese after the 2011 DEHP Food Scandal, Scientific Reports, 10.1038/srep45009, 7:1, Online publication date: 1-Dec-2017. Varshavsky J, Zota A and Woodruff T (2016) A Novel Method for Calculating Potency-Weighted Cumulative Phthalates Exposure with Implications for Identifying Racial/Ethnic Disparities among U.S. Reproductive-Aged Women in NHANES 2001–2012, Environmental Science & Technology, 10.1021/acs.est.6b00522, 50:19, (10616-10624), Online publication date: 4-Oct-2016. Cao Y, Liu J, Liu Y, Wang J and Hao X (2016) An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2015.11.019, 74, (34-41), Online publication date: 1-Feb-2016. Xie Z, Wang J, Dai F, Jin X, Wu K, Chen Q and Wang Y (2016) Effects of maternal exposure to di- n -butyl phthalate during pregnancy and breastfeeding on ovarian development and function of F1 female rats, Environmental Toxicology and Pharmacology, 10.1016/j.etap.2016.01.022, 43, (38-43), Online publication date: 1-Apr-2016. Wei B, Blount B, Xia B and Wang L (2015) Assessing exposure to tobacco-specific carcinogen NNK using its urinary metabolite NNAL measured in US population: 2011–2012, Journal of Exposure Science & Environmental Epidemiology, 10.1038/jes.2014.88, 26:3, (249-256), Online publication date: 1-May-2016. Fromme H, Gareis M, Völkel W and Gottschalk C (2016) Overall internal exposure to mycotoxins and their occurrence in occupational and residential settings – An overview, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2015.11.004, 219:2, (143-165), Online publication date: 1-Mar-2016. Tsai H, Wu C, Tsai Y, Huang P, Chen M, Wang S, Chen B, Chen C, Wu W, Hsu P, Hsiung C and Wu M (2016) Intake of Phthalate-tainted Foods and Serum Thyroid Hormones in Taiwanese Children and Adolescents, Scientific Reports, 10.1038/srep30589, 6:1, Online publication date: 1-Nov-2016. Xu R, Gao H, Zhu F, Cao W, Yan Y, Zhou X, Xu Q and Ji W (2016) SPE–UPLC–MS/MS for the determination of phthalate monoesters in rats urine and its application to study the effects of food emulsifier on the bioavailability of priority controlling PAEs, Journal of Chromatography B, 10.1016/j.jchromb.2016.01.007, 1012-1013, (97-105), Online publication date: 1-Feb-2016. Benjamin S, Pradeep S, Sarath Josh M, Kumar S and Masai E (2015) A monograph on the remediation of hazardous phthalates, Journal of Hazardous Materials, 10.1016/j.jhazmat.2015.05.004, 298, (58-72), Online publication date: 1-Nov-2015. Herrero L, Calvarro S, Fernández M, Quintanilla-López J, González M and Gómara B (2015) Feasibility of ultra-high performance liquid and gas chromatography coupled to mass spectrometry for accurate determination of primary and secondary phthalate metabolites in urine samples, Analytica Chimica Acta, 10.1016/j.aca.2014.09.043, 853, (625-636), Online publication date: 1-Jan-2015. Christensen K, Makris S and Lorber M (2014) Generation of hazard indices for cumulative exposure to phthalates for use in cumulative risk assessment, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2014.04.019, 69:3, (380-389), Online publication date: 1-Aug-2014. Lee J, Lee J, Kim C and Thomsen M (2014) Childhood exposure to DEHP, DBP and BBP under existing chemical management systems: A comparative study of sources of childhood exposure in Korea and in Denmark, Environment International, 10.1016/j.envint.2013.10.020, 63, (77-91), Online publication date: 1-Feb-2014. Ji Y, Wang F, Zhang L, Shan C, Bai Z, Sun Z, Liu L and Shen B (2014) A comprehensive assessment of human exposure to phthalates from environmental media and food in Tianjin, China, Journal of Hazardous Materials, 10.1016/j.jhazmat.2014.06.055, 279, (133-140), Online publication date: 1-Aug-2014. Leng G, Koch H, Gries W, Schütze A, Langsch A, Brüning T and Otter R (2014) Urinary metabolite excretion after oral dosage of bis(2-propylheptyl) phthalate (DPHP) to five male volunteers – Characterization of suitable biomarkers for human biomonitoring, Toxicology Letters, 10.1016/j.toxlet.2014.06.035, 231:2, (282-288), Online publication date: 1-Dec-2014. Christensen K, Sobus J, Phillips M, Blessinger T, Lorber M and Tan Y (2014) Changes in epidemiologic associations with different exposure metrics: A case study of phthalate exposure associations with body mass index and waist circumference, Environment International, 10.1016/j.envint.2014.07.010, 73, (66-76), Online publication date: 1-Dec-2014. Bhat V, Durham J and English J (2014) Derivation of an oral reference dose (RfD) for the plasticizer, di-(2-propylheptyl)phthalate (Palatinol® 10-P), Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2014.06.002, 70:1, (65-74), Online publication date: 1-Oct-2014. Fromme H, Lahrz T, Kraft M, Fembacher L, Mach C, Dietrich S, Burkardt R, Völkel W and Göen T (2014) Organophosphate flame retardants and plasticizers in the air and dust in German daycare centers and human biomonitoring in visiting children (LUPE 3), Environment International, 10.1016/j.envint.2014.06.016, 71, (158-163), Online publication date: 1-Oct-2014. Dewalque L, Charlier C and Pirard C (2014) Estimated daily intake and cumulative risk assessment of phthalate diesters in a Belgian general population, Toxicology Letters, 10.1016/j.toxlet.2014.06.028, 231:2, (161-168), Online publication date: 1-Dec-2014. Saravanabhavan G, Walker M, Guay M and Aylward L (2014) Urinary excretion and daily intake rates of diethyl phthalate in the general Canadian population, Science of The Total Environment, 10.1016/j.scitotenv.2014.08.089, 500-501, (191-198), Online publication date: 1-Dec-2014. Fong J, Lee F, Lu I, Uang S and Lee C (2014) Estimating the contribution of inhalation exposure to di-2-ethylhexyl phthalate (DEHP) for PVC production workers, using personal air sampling and urinary metabolite monitoring, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2013.04.002, 217:1, (102-109), Online publication date: 1-Jan-2014. Fromme H, Lahrz T, Kraft M, Fembacher L, Dietrich S, Sievering S, Burghardt R, Schuster R, Bolte G and Völkel W (2013) Phthalates in German daycare centers: Occurrence in air and dust and the excretion of their metabolites by children (LUPE 3), Environment International, 10.1016/j.envint.2013.09.006, 61, (64-72), Online publication date: 1-Nov-2013. Fromme H, Gruber L, Schuster R, Schlummer M, Kiranoglu M, Bolte G and Völkel W (2013) Phthalate and di-(2-ethylhexyl) adipate (DEHA) intake by German infants based on the results of a duplicate diet study and biomonitoring data (INES 2), Food and Chemical Toxicology, 10.1016/j.fct.2012.12.004, 53, (272-280), Online publication date: 1-Mar-2013. Magdouli S, Daghrir R, Brar S, Drogui P and Tyagi R (2013) Di 2-ethylhexylphtalate in the aquatic and terrestrial environment: A critical review, Journal of Environmental Management, 10.1016/j.jenvman.2013.04.013, 127, (36-49), Online publication date: 1-Sep-2013. Chen C, Chou Y, Wu Y, Lin C, Lin S and Lee C (2013) Phthalates may promote female puberty by increasing kisspeptin activity, Human Reproduction, 10.1093/humrep/det325, 28:10, (2765-2773), Online publication date: 1-Oct-2013. Kransler K, Bachman A and McKee R (2013) Estimates of daily di-isodecyl phthalate (DIDP) intake calculated from urinary biomonitoring data, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2012.11.004, 65:1, (29-33), Online publication date: 1-Feb-2013. Chen H, Chiang P, Wang Y, Kao M, Shieh T, Tsai C and Tsai E (2012) Benzyl butyl phthalate induces necrosis by AhR mediation of CYP1B1 expression in human granulosa cells, Reproductive Toxicology, 10.1016/j.reprotox.2011.11.004, 33:1, (67-75), Online publication date: 1-Jan-2012. Shi W, Hu X, Zhang F, Hu G, Hao Y, Zhang X, Liu H, Wei S, Wang X, Giesy J and Yu H (2012) Occurrence of Thyroid Hormone Activities in Drinking Water from Eastern China: Contributions of Phthalate Esters, Environmental Science & Technology, 10.1021/es202625r, 46:3, (1811-1818), Online publication date: 7-Feb-2012. Bang D, Kyung M, Kim M, Jung B, Cho M, Choi S, Kim Y, Lim S, Lim D, Won A, Kwack S, Lee Y, Kim H and Lee B (2012) Human Risk Assessment of Endocrine-Disrupting Chemicals Derived from Plastic Food Containers, Comprehensive Reviews in Food Science and Food Safety, 10.1111/j.1541-4337.2012.00197.x, 11:5, (453-470), Online publication date: 1-Sep-2012. Kransler K, Bachman A and McKee R (2012) A comprehensive review of intake estimates of di-isononyl phthalate (DINP) based on indirect exposure models and urinary biomonitoring data, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2012.01.001, 62:2, (248-256), Online publication date: 1-Mar-2012. Hines C, Hopf N, Deddens J, Silva M and Calafat A (2011) Occupational exposure to diisononyl phthalate (DiNP) in polyvinyl chloride processing operations, International Archives of Occupational and Environmental Health, 10.1007/s00420-011-0674-z, 85:3, (317-325), Online publication date: 1-Apr-2012. Nishioka J, Iwahara C, Kawasaki M, Yoshizaki F, Nakayama H, Takamori K, Ogawa H and Iwabuchi K (2011) Di-(2-ethylhexyl) phthalate induces production of inflammatory molecules in human macrophages, Inflammation Research, 10.1007/s00011-011-0390-x, 61:1, (69-78), Online publication date: 1-Jan-2012. Pan G, Hanaoka T, Yu L, Na J, Yamano Y, Hara K, Ichiba M, Nakadate T, Kishi R, Wang P, Yin H, Zhang S and Feng Y (2011) Associations between hazard indices of di-n-butylphthalateand di-2-ethylhexylphthalate exposure and serum reproductive hormone levels among occupationally exposed and unexposed Chinese men, International Journal of Andrology, 10.1111/j.1365-2605.2011.01201.x, 34:5pt2, (e397-e406), Online publication date: 1-Oct-2011. Clark K, David R, Guinn R, Kramarz K, Lampi M and Staples C (2011) Modeling Human Exposure to Phthalate Esters: A Comparison of Indirect and Biomonitoring Estimation Methods, Human and Ecological Risk Assessment: An International Journal, 10.1080/10807039.2011.588157, 17:4, (923-965), Online publication date: 1-Jul-2011. Gaudin R, Marsan P, Ndaw S, Robert A and Ducos P (2010) Biological monitoring of exposure to di(2-ethylhexyl) phthalate in six French factories: a field study, International Archives of Occupational and Environmental Health, 10.1007/s00420-010-0566-7, 84:5, (523-531), Online publication date: 1-Jun-2011. Lorber M, Koch H and Angerer J (2010) A critical evaluation of the creatinine correction approach: Can it underestimate intakes of phthalates? A case study with di-2-ethylhexyl phthalate, Journal of Exposure Science & Environmental Epidemiology, 10.1038/jes.2010.43, 21:6, (576-586), Online publication date: 1-Nov-2011. Suzuki Y, Niwa M, Yoshinaga J, Mizumoto Y, Serizawa S and Shiraishi H (2010) Prenatal exposure to phthalate esters and PAHs and birth outcomes, Environment International, 10.1016/j.envint.2010.05.003, 36:7, (699-704), Online publication date: 1-Oct-2010. Koch H and Calafat A (2009) Human body burdens of chemicals used in plastic manufacture, Philosophical Transactions of the Royal Society B: Biological Sciences, 10.1098/rstb.2008.0208, 364:1526, (2063-2078), Online publication date: 27-Jul-2009. Saillenfait A, Sabaté J and Gallissot F (2009) Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat, Reproductive Toxicology, 10.1016/j.reprotox.2009.06.013, 28:4, (468-476), Online publication date: 1-Dec-2009. Kamrin M (2009) Phthalate Risks, Phthalate Regulation, and Public Health: A Review, Journal of Toxicology and Environmental Health, Part B, 10.1080/10937400902729226, 12:2, (157-174), Online publication date: 4-Mar-2009. Yan X, Calafat A, Lashley S, Smulian J, Ananth C, Barr D, Silva M, Ledoux T, Hore P and Robson M (2009) Phthalates Biomarker Identification and Exposure Estimates in a Population of Pregnant Women, Human and Ecological Risk Assessment: An International Journal, 10.1080/10807030902892554, 15:3, (565-578), Online publication date: 9-Jun-2009. Kwack S, Kim K, Kim H, Yoon K and Lee B (2009) Risk Assessment of Soybean-Based Phytoestrogens, Journal of Toxicology and Environmental Health, Part A, 10.1080/15287390903212212, 72:21-22, (1254-1261), Online publication date: 30-Sep-2009. Cowan-Ellsberry C and Robison S (2009) Refining Aggregate Exposure: Example using Parabens, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2009.08.004, 55:3, (321-329), Online publication date: 1-Dec-2009. Benson R (2009) Hazard to the developing male reproductive system from cumulative exposure to phthalate esters—dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2008.11.005, 53:2, (90-101), Online publication date: 1-Mar-2009. Hernández-Díaz S, Mitchell A, Kelley K, Calafat A and Hauser R (2008) Medications as a Potential Source of Exposure to Phthalates in the U.S. Population, Environmental Health Perspectives, 117:2, (185-189), Online publication date: 1-Feb-2009. Chen M, Chen J, Tang C and Mao I (2008) The internal exposure of Taiwanese to phthalate—An evidence of intensive use of plastic materials, Environment International, 10.1016/j.envint.2007.07.004, 34:1, (79-85), Online publication date: 1-Jan-2008. Franco A, Prevedouros K, Alli R and Cousins I (2007) Comparison and analysis of different approaches for estimating the human exposure to phthalate esters, Environment International, 10.1016/j.envint.2006.10.001, 33:3, (283-291), Online publication date: 1-Apr-2007. Fromme H, Gruber L, Schlummer M, Wolz G, Böhmer S, Angerer J, Mayer R, Liebl B and Bolte G (2007) Intake of phthalates and di(2-ethylhexyl)adipate: Results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data, Environment International, 10.1016/j.envint.2007.05.006, 33:8, (1012-1020), Online publication date: 1-Nov-2007. Nakazawa H, Ito R, Iwasaki Y, Nakata A and Saito K (2007) Trace Analysis of Endocrine Disrupting Chemicals for Risk Assessment to Human Exposure, Bunseki kagakuBUNSEKI KAGAKU, 10.2116/bunsekikagaku.56.1005, 56:12, (1005-1018), . Wittassek M, Heger W, Koch H, Becker K, Angerer J and Kolossa-Gehring M (2007) Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children – A comparison of two estimation models based on urinary DEHP metabolite levels, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2006.11.009, 210:1, (35-42), Online publication date: 1-Feb-2007. Koch H, Becker K, Wittassek M, Seiwert M, Angerer J and Kolossa-Gehring M (2006) Di-n-butylphthalate and butylbenzylphthalate — urinary metabolite levels and estimated daily intakes: pilot study for the German Environmental Survey on children, Journal of Exposure Science & Environmental Epidemiology, 10.1038/sj.jes.7500526, 17:4, (378-387), Online publication date: 1-Jul-2007. Wittassek M, Wiesmüller G, Koch H, Eckard R, Dobler L, Müller J, Angerer J and Schlüter C (2007) Internal phthalate exposure over the last two decades – A retrospective human biomonitoring study, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2007.01.037, 210:3-4, (319-333), Online publication date: 1-May-2007. Koch H and Angerer J (2007) Di-iso-nonylphthalate (DINP) metabolites in human urine after a single oral dose of deuterium-labelled DINP, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2006.11.008, 210:1, (9-19), Online publication date: 1-Feb-2007. Ross G (2016) A Perspective on the Safety of Cosmetic Products: A Position Paper of The American Council on Science and Health, International Journal of Toxicology, 10.1080/10915810600746049, 25:4, (269-277), Online publication date: 1-Jul-2006. McKee R, Pavkov K, Trimmer G, Keller L and Stump D (2006) An assessment of the potential developmental and reproductive toxicity of di-isoheptyl phthalate in rodents, Reproductive Toxicology, 10.1016/j.reprotox.2005.09.002, 21:3, (241-252), Online publication date: 1-Apr-2006. Marsee K, Woodruff T, Axelrad D, Calafat A and Swan S (2006) Estimated Daily Phthalate Exposures in a Population of Mothers of Male Infants Exhibiting Reduced Anogenital Distance, Environmental Health Perspectives, 114:6, (805-809), Online publication date: 1-Jun-2006.Weuve J, Sánchez B, Calafat A, Schettler T, Green R, Hu H and Hauser R (2006) Exposure to Phthalates in Neonatal Intensive Care Unit Infants: Urinary Concentrations of Monoesters and Oxidative Metabolites, Environmental Health Perspectives, 114:9, (1424-1431), Online publication date: 1-Sep-2006.Albertini R, Bird M, Doerrer N, Needham L, Robison S, Sheldon L and Zenick H (2006) The Use of Biomonitoring Data in Exposure and Human Health Risk Assessments, Environmental Health Perspectives, 114:11, (1755-1762), Online publication date: 1-Nov-2006.Calafat A and McKee R (2006) Integrating Biomonitoring Exposure Data into the Risk Assessment Process: Phthalates [Diethyl Phthalate and Di(2-ethylhexyl) Phthalate] as a Case Study, Environmental Health Perspectives, 114:11, (1783-1789), Online publication date: 1-Nov-2006. Itoh H, Yoshida K and Masunaga S (2005) Evaluation of the effect of governmental control of human exposure to two phthalates in Japan using a urinary biomarker approach, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2005.02.004, 208:4, (237-245), Online publication date: 1-Jul-2005. Jung Koo H and Mu Lee B (2005) Human Monitoring of Phthalates and Risk Assessment, Journal of Toxicology and Environmental Health, Part A, 10.1080/15287390590956506, 68:16, (1379-1392), Online publication date: 1-Aug-2005. Koch H, Angerer J, Drexler H, Eckstein R and Weisbach V (2005) Di(2-ethylhexyl)phthalate (DEHP) exposure of voluntary plasma and platelet donors, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2005.07.001, 208:6, (489-498), Online publication date: 1-Nov-2005. McKee R, Butala J, David R and Gans G (2004) NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps, Reproductive Toxicology, 10.1016/j.reprotox.2003.09.002, 18:1, (1-22), Online publication date: 1-Jan-2004. Koch H, Drexler H and Angerer J (2004) Response to the letter of R. M. David Int. J. Hyg. Environ. Health 207, 75 – 76 (2004), International Journal of Hygiene and Environmental Health, 10.1078/1438-4639-00272, 207:1, (77-78), Online publication date: 1-Jan-2004. McKee R, Butala J, David R and Gans G (2004) Response to Dr. Koch’s letter, Reproductive Toxicology, 10.1016/j.reprotox.2004.05.007, 18:6, (761-764), Online publication date: 1-Aug-2004. Tyl R, Myers C, Marr M, Fail P, Seely J, Brine D, Barter R and Butala J (2004) Reproductive toxicity evaluation of dietary butyl benzyl phthalate (BBP) in rats, Reproductive Toxicology, 10.1016/j.reprotox.2003.10.006, 18:2, (241-264), Online publication date: 1-Mar-2004. Babich M, Chen S, Greene M, Kiss C, Porter W, Smith T, Wind M and Zamula W (2004) Risk assessment of oral exposure to diisononyl phthalate from children’s products, Regulatory Toxicology and Pharmacology, 10.1016/j.yrtph.2004.06.005, 40:2, (151-167), Online publication date: 1-Nov-2004. David R (2004) Commentary regarding the article by Koch et al.: An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population. Int. J. Hyg. Environ. Health, 206, 77 – 83 (2003), International Journal of Hygiene and Environmental Health, 10.1078/1438-4639-00271, 207:1, (75-76), Online publication date: 1-Jan-2004. Kessler W, Numtip W, Grote K, Csanády G, Chahoud I and Filser J (2004) Blood burden of di(2-ethylhexyl) phthalate and its primary metabolite mono(2-ethylhexyl) phthalate in pregnant and nonpregnant rats and marmosets, Toxicology and Applied Pharmacology, 10.1016/j.taap.2003.11.014, 195:2, (142-153), Online publication date: 1-Mar-2004. Barlow N and Foster P (2016) Pathogenesis of Male Reproductive Tract Lesions from Gestation Through Adulthood Following in Utero Exposure to Di(n-butyl) Phthalate, Toxicologic Pathology, 10.1080/01926230390202335, 31:4, (397-410), Online publication date: 1-Jun-2003. Barr D, Silva M, Kato K, Reidy J, Malek N, Hurtz D, Sadowski M, Needham L and Calafat A (2003) Assessing human exposure to phthalates using monoesters and their oxidized metabolites as biomarkers., Environmental Health Perspectives, 111:9, (1148-1151), Online publication date: 1-Jul-2003. McKee R, El-Hawari M, Stoltz M, Pallas F and Lington A (2002) Absorption, disposition and metabolism of di-isononyl phthalate (DINP) in F-344 rats, Journal of Applied Toxicology, 10.1002/jat.861, 22:5, (293-302), Online publication date: 1-Sep-2002. (2002) Toxicological Profile for DI(2-Ethylhexyl)Phthalate ATSDR's Toxicological Profiles, 10.1201/9781420061888_ch70, Online publication date: 12-Jan-2002. Kawaguchi M, Funabashi T, Aiba S and Kimura F (2002) Butyl Benzyl Phthalate, an Endocrine Disrupter, Inhibits Pulsatile Luteinizing Hormone Secretion Under an Insulin-Induced Hypoglycaemic State in Ovariectomized Rats, Journal of Neuroendocrinology, 10.1046/j.1365-2826.2002.00804.x, 14:6, (486-491) Rettenmeier A, Drexler H and Hartwig A (2018) Di-(2-ethylhexyl)phthalat (DEHP) [BAT Value Documentation in German language, 2018] The MAK-Collection for Occupational Health and Safety, 10.1002/3527600418.bb11781d0023, (878-893) Kim Y, Kho Y, Chun K, Koh J, Park J, Bunderson-Schelvan M and Cho Y (2016) Increased Urinary Phthalate Levels in Women with Uterine Leiomyoma: A Case-Control Study, International Journal of Environmental Research and Public Health, 10.3390/ijerph13121247, 13:12, (1247) Christensen K and Lorber M (2014) Exposure to BPA in Children—Media-Based and Biomonitoring-Based Approaches, Toxics, 10.3390/toxics2020134, 2:2, (134-157) David R, Bachman A, Butala J, Piper J and Shelp C (2012) Esters of Mono-, Di-, and Tricarboxylic Acids Patty's Toxicology, 10.1002/0471435139.tox080.pub2, (147-352) Gao H, Xu R, Cao W, Zhou X, Yan Y, Lu L, Xu Q, Shen Y and Hussain S (2016) Food Emulsifier Glycerin Monostearate Increases Internal Exposure Levels of Six Priority Controlled Phthalate Esters and Exacerbates Their Male Reproductive Toxicities in Rats, PLOS ONE, 10.1371/journal.pone.0161253, 11:8, (e0161253) Vol. 108, No. 10 October 2000Metrics About Article Metrics Publication History Originally published1 October 2000Published in print1 October 2000 Financial disclosuresPDF download License information EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. 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