Abstract
BackgroundFew studies have been published related to the analysis of different skin aging parameters for whole-body skin using the SCINEXA scale for skin damage. The aim of this study was to evaluate the reproducibility of the SCINEXA scale (SCore for INtrinsic and EXtrinsic skin Aging) in South-Americans non-Caucasian population of a region of Ecuador.MethodsExploratory observational study. Thirty subjects of both genders, over 40 years old and living in a rural area with particular characteristics regarding sun exposure were included. The SCINEXA scale was applied at three different time points to assess its reproducibility. Repeated measures analysis of variance was used for comparison of mean SCINEXA scores. Intraclass correlation coefficient, 95% CI and “Cronbach’s alpha” coefficient were performed to measure reproducibility.ResultsAmong participants, 86.7% were female; mean age was over 67 years old, with mainly low educational level, and almost half had more than six hours of sun exposure per day. Test-retest reproducibility of this scale demonstrated almost perfect agreement. The SCINEXA score was greater than 2 points in half of the subjects, reflecting aging due to sun exposure.LimitationsMost participants were women from one town in a particular geographical area, and the sample size was small. Genetic determinants of skin phenotypes were not assessed.ConclusionsThe SCINEXA score is reproducible in South American non-Caucasian subjects of a particular region of the country. Damage from sun exposure was evident in participants.
Highlights
Few studies have been published related to the analysis of different skin aging parameters for wholebody skin using the SCore for INtrinsic and EXtrinsic skin Aging (SCINEXA) scale for skin damage
The SCINEXA score is reproducible in South American non-Caucasian subjects of a particular region of the country
Damage from sun exposure was evident in participants
Summary
Few studies have been published related to the analysis of different skin aging parameters for wholebody skin using the SCINEXA scale for skin damage. The aim of this study was to evaluate the reproducibility of the SCINEXA scale (SCore for INtrinsic and EXtrinsic skin Aging) in South-Americans non-Caucasian population of a region of Ecuador. The appearance of malignant and premalignant skin lesions is sun- exposure related, and these lesions constituted the second highest prevalent group of neoplasms, for both males and females, in the population of the city of Quito, Ecuador [1]. The data are limited because there are not enough studies in Ecuador regarding photo damage, despite the city being in one of the regions with the highest exposure to ultraviolet radiation. Some descriptive skin-aging scales have been developed to assess skin aging signs, but Vierkotter et al [3], published the results of the development of the SCINEXA scale (SCore for INtrinsic and EXtrinsic skin Aging), which measures these intrinsic and extrinsic factors regarding chronological skin aging and aging due to chronic exposure to ultraviolet (UV) radiation, respectively
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