Abstract
BackgroundThe objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults.MethodsA cross-sectional survey was sent to a randomly selected population sample of 78,004 adults in Sweden. The questionnaires included measures of self-reported physical and mental health. Binary and multinomial logistic regression were used to examine the associations of AD with common chronic health conditions and psychological wellbeing.ResultsAD was self-reported by 4,175 respondents, representing almost 14% of the study population of 34,313 adults. Our results showed positive associations between AD and chronic health disorders, including conditions of the oral cavity: chronic obstructive pulmonary disease (adjusted odds ratio [aOR] = 1.58, 95% confidence interval [CI]: 1.30 to 1.92), asthma (aOR = 2.13, 95% CI: 1.91 to 2.38), mild recurrent gastrointestinal symptoms (adjusted relative risk ratio [aRRR] = 1.78, 95% CI: 1.64 to 1.92), high blood pressure (aOR = 1.16, 95% CI: 1.06 to 1.26), obesity (aOR = 1.34, 95% CI: 1.23 to 1.47), mild joint pain (aRRR = 1.47, 95% CI: 1.35 to 1.61), mild headache or migraine (aRRR = 1.50, 95% CI: 1.38 to 1.64), caries (aOR = 1.25, 95% CI: 1.04 to 1.49), bleeding gums (aOR = 1.69, 95% CI: 1.38 to 2.08), periodontitis (aOR = 1.42, 95% CI: 1.13 to 1.77), sensitive teeth (aOR = 1.57, 95% CI: 1.35 to 1.82), and dry mouth (aOR = 1.52, 95% CI: 1.33 to 1.74). Adjustment for asthma and depression attenuated the magnitude of the associations between AD and the study outcomes. AD was also associated with poorer general psychological wellbeing.ConclusionsAdults reporting AD may be at increased risk of chronic disorders and decreased psychological wellbeing. Physicians should recognize that individuals with severe AD and those with comorbid asthma or depression may be especially vulnerable.
Highlights
The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults
Asthma has been linked to AD, but, to the best of our knowledge, no studies have assessed the possible association between AD and chronic obstructive pulmonary disease (COPD), which affects the epithelial tissues of the airways
This study demonstrated that adults in Sweden with AD have an increased prevalence of self-reported chronic health conditions such as COPD, asthma, recurrent gastrointestinal symptoms, high blood pressure, obesity, Table 2 The associations between atopic dermatitis and study outcomes for 33 516 adolescents
Summary
The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults. Atopic dermatitis (AD) is a chronic inflammatory skin disease common in children and adults, with a lifetime prevalence of about 10–20% [1]. This itchy skin disease, which may have a negative impact on the quality of life of people with the disease and their families, accounts for the largest global health burden caused by a skin disease [2, 3]. There is increasing evidence of the co-occurrence of common chronic diseases in individuals with AD [5]. Co-occurrence of migraine has been observed in individuals with AD [7, 8]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.