Abstract
Background: The process of skin aging is a complex biological phenomenon consisting of two components, referred to as intrinsic and extrinsic aging, respectively. There are currently several studies that research probiotics as alternative therapeutic options for aging skin. Content: Skin aging in an individual is a combination of intrinsic and extrinsic skin aging. Intrinsic skin aging is a natural process that occurs with age, influenced by ethnicity, gender, gene, hormon, etc, while the extrinsic skin aging is influenced by environmental factors, such as life style, pollution, and especially ultraviolet radiation (photoaging). Probiotics are defined as live microorganisms that when administered in adequate amounts confer a health benefit to the host. Major probiotic mechanisms of action include enhancement of the epithelial barrier, increased adhesion to intestinal mucosa, and concomitant inhibition of pathogen adhesion, competitive exclusion of pathogenic microorganisms, production of anti-microorganism substances and modulation of the immune system. Conclusion: Aging is a natural process that we cannot avoid, so probiotics are an alternative therapy to slow down the skin aging process, both intrinsic and extrinsic. Probiotics can decrease MMP (matrix metalloproteinases) level, which is one of the factors that play a role in skin aging.
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