Abstract
Introducción: La leptospirosis es una enfermedad zoonótica causada por Leptospira interrogans y es transmitida por contacto directo con secreciones animales o agua contaminada. Veterinarios y estudiantes de medicina veterinaria son población en riesgo de adquirir la infección.
 Objetivo: Determinar la seroprevalencia de infección por Leptospira interrogans entre estudiantes de una facultad de medicina veterinaria en Bogotá, Colombia.
 Métodos: Se procesaron 445 sueros por ELISA, de los cuales 42 muestras se analizaron mediante microaglutinación (MAT).
 Resultados: La seroprevalencia a Leptospira por ELISA IgM fue del 7,9 % (35de 445). De ellos 34 sueros fueron positivos por MAT al menos para un serovar.
 Conclusión: Este estudio confirma la utilidad del diagnóstico serológico en individuos con riesgo ocupacional para adquirir la leptospirosis y resalta la importancia del uso de barreras de protección para todas las poblaciones que tienen contacto regular con animales, incluidos los estudiantes de medicina veterinaria.
Highlights
Leptospirosis is a zoonotic disease caused by Leptospira interrogans and is transmitted by direct contact with animal secretions or contaminated water
This study confirms the usefulness of serological diagnosis in individuals with occupational risk for Leptospirosis and stand out the importance of using protective barriers by all populations who have regular animal contact including veterinary students
In order to assess the sera, we tested each sample by IgM-ELISA test (Panbio®) [3,6], and positive samples were subjected to microagglutination (MAT) on six Leptospira serovars (Hardjo, Pomona, Canicola, Tarassovi, Bratislava, Icterohaemorrahagiae) [3,7]
Summary
Leptospirosis is a zoonotic disease caused by Leptospira interrogans and is transmitted by direct contact with animal secretions or contaminated water. Veterinary and veterinary students are population at risk of infection. Objective: To determine the seroprevalence of Leptospira interrogans infection among students in a School of Veterinary Medicine in Bogotá, Colombia. Conclusion: This study confirms the usefulness of serological diagnosis in individuals with occupational risk for Leptospirosis and stand out the importance of using protective barriers by all populations who have regular animal contact including veterinary students. Transmission occurs by direct or indirect contact with secretions or material contaminated with the urine of these reservoirs. Infection is related with animal contact in occupational activities such as veterinarians, farmers, slaughterhouse, and rural workers [4,5]
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