Evaluations of haematological profile in geriatric patients in a tertiary care hospital

Abstract

Ageing is the process which has an impact on all the cells, tissues, organ systems, and organisms. Alterations or modifications in the bone marrow are observed with ageing. Increased risk of myeloproliferative disorders, anaemia, and a deteriorating adaptive immunity are signs of age-related hematologic alterations, as is a loss in bone marrow cellularity. Evaluations of haematological parameters can be used to track the disease's development. Hence, this retrospective study was designed to evaluate the haematological profile of geriatric patients and to compare the haematological parameters between males and females. The Complete Blood Count reports of 445 patients aged 60 years and above were selected for this retrospective study. The backbone computerized data of these cases were taken from central laboratory of Yenepoya Medical College Hospital. Haematological profile was studied and analyzed from selected cases. The independent sample t test was used to compare the haematological parameters of males and females.P value<0.05 was considered as significant.The results obtained showed that there was a statistical significance in lymphocytes, Eosinophils, MCH, MCHC in Geriatrics patients. There was no statistical significance in haemoglobin, neutrophils, monocytes, platelet count, MCV, PCV, and RBC count .Major abnormalities were found in Haemoglobin and lymphocytes than other haematological parameters. Incidence of anaemia was 77.8% and lymphocytopenia 77.9%.The most frequently observed haematological abnormalities in elderly persons were anaemia and lymphocytopenia. Anaemia was seen to be higher in females than males. Lymphocytopenia was seen to be higher in males than females. Early evaluations of haematological profile will reduce morbidity and mortality among the geriatric patients.