Evaluation of wound healing activity of Dhataki Pushpa ointment (Woodfordia fruticosa Kurz.) on Sadyavrana (excised wound) - An experimental study

Abstract

Background: Woodfordia fruiticosa Kurz. of Lythraceae is a shrub whose blooms are called Dhataki Kusuma. The fresh flower of W. fruticosa controls bleeding in emergency cuts, whereas the dried flower powder heals wounds faster. Indian tribes utilise it to cure wounds. No scientific evidence supported using W. fruticosa to treat wounds, hence the present study assessed the plant's wound healing ability. Aim: To find out the efficacy of Dhataki Pushpa ointment on Sadyavrana (excised wound). Material & Methodology: BSI (Botanical Survey of India) verified Dhataki flowers. The ointment was prepared and then standardised. This research randomly chose 12 Wistar rats (six for Dhataki Pushpa ointment, and six for betadine). Albino rats (Wistar) of both sexes weighing 150-200 g were used in this research to examine the impact of Dhataki Pushpa ointment on the healing of Sadyavrana (incised wound). Observations: Progressively wound contraction was assessed on 0 days, 4th, 8th, 12th, and 16th days in both groups using graph paper (mm2) and represented as a percentage. Result: the statistical analysis (unpaired t-test) revealed that there is a significant difference in the wound healing activity of both the ointments on Sadyavrana (p<0.0001). Discussion: Dhataki extract is antibacterial and antifungal. Tannins and alcohol concentration may speed wound contraction and healing. Reduced wound contraction indicates Dhataki ointment's superiority over betadine. Conclusion: Dhataki flower ointment has a significant effect on Sadyavrana when compared with betadine ointment.