Evaluation of the relationship between pump duration and arterial blood gases in patients undergoing on-pump CABG

Abstract

Introduction: Arterial blood gas (ABG) is one of the most important laboratory tests to determine the pH status, oxygen and carbon dioxide levels of the blood and bicarbonate levels. Lactate, hemoglobin and electrolyte levels can also be obtained from this test. Changes in these items can be important steps in determining the relationship between these changes and the complications of various organs. so, the aim of this study was to investigate the relationship between pump duration and arterial blood gases in patients undergoing on-pump CABG. Material and Methods: During the surgery, the exact time of the pump time, patients' cross-clamping and questionnaires were recorded by the responsible resident. Arterial blood samples were taken from all patients before and 45 minutes after anesthesia, after removal of the cardiopulmonary pump, one hour after admission to the ICU, 1 hour and 6 hours after extubation, and three days after admission to open heart ICU. ABG parameters including PO2, PCO2, PH and HCO3 were measured each time. Finally, the relationship between pump time and ABG parameters was assessed using the obtained data and designed questionnaire. Data were analyzed by IBM SPSS Statistics V22.0. Results: ABG parameters in the two pump time groups were not statistically significant before anesthesia, during surgery, ICU admission time, one hour after open heart ICU admission and one hour after patient extubation (P> 0.05). PCO2 in the long pump time group was relatively decreased 6 hours and 3 days after admission to the open heart ICU and patients showed some degree of respiratory alkalosis (P = 0.04). Conclusion: Our findings show that preoperative and postoperative ABG analysis is an important factor in patients undergoing CABG and its correct interpretation can manage postoperative complications.