Evaluation Of Some Biochemical Parameters In Patients With Breast Cancer In Basrah Governorate

Abstract

Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women. Breast cancer is the second leading cause of cancer deaths among women . In Iraq, breast cancer is the commonest type of female malignancy, ac-counting for approximately one-third of the registered female cancers according to the latest Iraqi Cancer Registry. In this study, patients and volunteers from Basrah Governorate (southern Iraq) participated. A total of fifty five participants were subdivided into two groups, breast cancer patients 35 aged (20-60) years, and 20 healthy individuals (control group) aged (20-60) years. Serum levels of Estrogen , Progesterone , glutathione peroxidase, superoxide dismutase , immunoglobulinG , immunoglobulinM and cancer antigen 15-3 were measured by standard methods. The study reported that Progesterone and IgG were statistically significant (p˂0.05) in patients with breast cancer compared to healthy control . Estrogen, glutathione peroxidase and superoxide dismutase were statistically very high significant (p ≤0.0001) in patients with breast cancer compared to healthy control .There was very high significant positive correlation between estrogen and IgM (p ≤0.0001) .