Evaluation of posterior segment manifestations following typhoid fever-a clinical study

Abstract

Aim: To describe fundus manifestations following typhoid fever and their response to systemic steroids. Materials and Methods: A retrospective study was done on 14 patients during April 2015-Feb 2016 presenting with complaints of diminution of vision with history of typhoid fever 4-6 weeks ago. All patients underwent a detailed ophthalmic evaluation. OCT and FFA were done when considered relevant. TC/DC/ESR/ HIV and Widal tests were done. Oral prednisolone, 1mg/kg/day was given and tapered over a period of 6 weeks. Results: 21 eyes of 14 patients presenting with visual complaints following typhoid fever were studied. At presentation, vision was Conclusion: Even though a less documented entity, one can encounter non-infectious immune mediated retinitis after typhoid fever. This study highlights the need for a high index of suspicion to diagnose this condition and early institution of steroids for better visual outcome. Keywords: Steroids, Post-febrile neuroretinitis, Typhoid, Post-typhoid retinitis, Widal titres.