Abstract
Evaluation of in vitro antimicrobial effects of Azadirachta indica (Neem) leaves extracts against selected pathogens
Highlights
Antibiotics provide the basis for the fungal and bacterial infections therapy
Indiscriminate use of antibiotics in human and veterinary healthcare systems has lead to the emergence of multi-drug resistant (MDR) strains of different groups of microorganisms [1,2] .The emergence and dissemination of MDR bacteria has made chemically synthesized antibiotics ineffective for the treatment of infectious diseases caused by such bacteria [3]
The effect of different concentrations of petroleum ether and methanol extracts of Neem leaves (A.indica) against bacteria was determined by disc diffusion method, and varying of results were obtained of our experiment according to the solvent of extract used and its concentration and the type of bacteria
Summary
Antibiotics provide the basis for the fungal and bacterial infections therapy. The discovery of antibiotics and making use of them as chemotherapeutic agents has made the medical fraternity to believe that they will eradicate various infectious diseases. Indiscriminate use of antibiotics in human and veterinary healthcare systems has lead to the emergence of multi-drug resistant (MDR) strains of different groups of microorganisms [1,2] .The emergence and dissemination of MDR bacteria has made chemically synthesized antibiotics ineffective for the treatment of infectious diseases caused by such bacteria [3]. These circumstances have propelled the researchers and scientists to explore new antimicrobial substances from various sources such as medicinal plants [4]. Conclusions: The result obtained indicate the leaves extracts of Neem plant have enormous antimicrobial effect, and may be exploited for the treatment of various infectious diseases
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