Abstract

In our current work, we have focused on AgNPs biosynthesis from the ethanolic leaf extract of Tinospora cordifolia and evaluated for their antioxidant, hepato and nephro-protective effects. The results depicted significant restoration in the serum levels of urea, creatine, and uric acid, SGOT and SGPT in potassium bromate induced Swiss albino mice to its normalcy upon treatment with AgNPs. The histopathological study on the kidney tissues correlates well with our biochemical observations. The overall results revealed that the synthesized AgNPs possess strong antioxidant, hepato and nephro-protectivity and directed towards the clinical use as a therapeutic agent.

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