Evaluation of blood pressure using a flexible and wearable capacitive pressure sensor.

Abstract

In recent times, the high demand for flexible and wearable pressure sensors to monitor human health, particularly for patients afflicted with hypertension or high blood pressure (BP), has captured the keen interest of researchers. Capacitance-based flexible sensing devices offer real-time metrics regarding vital physiological parameters of the human body, such as BP and pulse rate (PR), thereby enabling the identification of cardiovascular complications. In this regard, we have developed a capacitive pressure sensor using polydimethylsiloxane (PDMS) and deionized water (DIW) and improved its key parameters by adding baking powder to PDMS-DIW. The sensor demonstrated excellent performance in static pressure measurements with a sensitivity of 0.021 Pa-1, detection limit of 1 Pa, and response time of 100 ms. We further investigated its application in human BP monitoring. The sensor successfully captured the oscillometric waveform (OMW) for all 160 participants and demonstrated excellent performance in accurately measuring BP, meeting all criteria outlined as the universal standard when compared with the reference devices: OMRON BP device and the gold-standard mercury-based sphygmomanometer. Furthermore, the sensor accurately provided the PR and agreed well with the reference BP device. Therefore, the developed BP sensor can be a viable alternative to replace the pressure sensors in existing BP devices.