Abstract

The synthesis and utilization of Fe2O3 nanoparticles are increasing due to their low cost, environmentally friendly, and biocompatible nature. Antimicrobial resistance is noticed as a global health concern by the community. Multidrug therapy and improper treatment of any disease cause an exponential increase in resistant microbial species. Therefore, improving the treatment schemes for curing different types of contagious ailments caused by microbes is essential. An economical co-precipitation technique was utilized for the preparation of Fe2O3 nanoparticles. The Fe2O3 nanostructures were analyzed by FTIR, ultraviolet-visible spectroscopy, XRD, and TEM techniques. The Fe2O3 nanoparticle's dimensions were determined to be 28.72 nm. A toxicity study of these Fe2O3 nanoparticles was carried out against a Gram-negative bacterium Vibrio vulnificus and showed toxic properties towards the Vibrio vulnificus. The antibacterial properties of these Fe2O3 nanoparticles were contrasted with commonly used antibiotics, including chloramphenicol, streptomycin, ampicillin, penicillin, Tetracycline, sulphatriad, Co-Trimoxazole, Clindamycin, Oxacillin, Erythromycin, and Chloramphenicol, etc., and found to be comparable in some cases even better antibacterial activity.

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