Abstract
Theoretical calculations of the excitation functions for the reaction 67 Zn(p,n) 67 Ga on natural and enriched zinc targets for the energy range from threshold up to 18 MeV are carried out using nuclear reaction models from program packages EMPIRE-3 and TALYS 1.4. The results of calculations are compared with available experimental data. The yields of gallium isotopes produced by the reaction 67 Zn(p,n) 67 Ga on the proton beam of the cyclotron C18, IBA Belgium energy 18 MeV and current 30 μA are evaluated. Our calculations indicate that the yield of isotope 67 Ga in case of natural and enriched zinc targets are expected to be 23.6 MBq/µA*h and 139 MBq/µA*h, respectively.
Highlights
The study of nuclear reactions with intermediate or high energy protons is very important because it provides a basis for a wide range of technical applications
Depending of the type of radiation, the diagnostic isotopes are classified into two groups: β+-emitters (13N, 15O, 18F, 62Cu, 68Ga, etc.) used in Positron Emission Tomography (PET), and γ–emitters (67Ga, 99mTc, 123I, etc.) used in Single Photon Emission Computed Tomography (SPECT)
According to the information of World Health Organization (WHO) 8.2 million people worldwide died from cancer in 2012
Summary
The study of nuclear reactions with intermediate or high energy protons is very important because it provides a basis for a wide range of technical applications. The 67Ga commonly is used in SPECT investigations as a trivalent citrate compound for nuclear medicine imaging, and it is a valuable agent in the detection and localization of certain neoplasms and inflammatory lesions. It is well known when 67Ga is in the citrate form it is concentrated in many types of tumors, as well as non-malignant lesions. In the radioisotope production procedure, the nuclear reaction data are mainly needed for respective optimization of production rates This process involves a selection of the projectile energy range that will maximize the yield of produced isotopes and minimize the radioactive impurities.
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