Abstract
1. 1. Lipoproteins, like other macromolecules, will band on a density gradient at a position which corresponds to their hydrated density. Analysis of such banding patterns can yield estimates of the number of components, their apparent molecular weight, and their density. Coupled with other information, estimates of density heterogeneity are possible. 2. 2. We present the theory and method of calculation to analyze equilibrium density gradient banding patterns. We also give an example of a low-density lipoprotein pattern containing two components. 3. 3. Determination of the compressibility of low-density lipoproteins showed a value close to that of the aqueous solvent system.
Published Version
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