Epigenetic and neuroplasticity in neurodevelopmental disorders: possibilities of physical exercise

Abstract

This article deals with the relationship between the mechanisms of neuroplasticity and epigenetics provided through the regular practice of physical exercise for the treatment of neurodevelopmental disorders. The aim of the study was to focus on the benefits of early interventions, especially physical exercise, in cases of neurodevelopmental disorders through epigenetic and neuroplasticity mechanisms. For this, a critical review of a narrative nature was carried out in the Scielo, PubMed and PsycInfo databases, as well as consultation in books on the subject. The results show us that exercise seems to promote epigenetic improvements, which can prevent the onset of neurodevelopmental disorders and also promote changes through neuroplasticity, which can mitigate the deficits caused by pathologies, especially if it occurs during early childhood. We can then understand that exercise tends to improve neurodevelopment, but a more robust base of empirical studies on this subject is needed.