Abstract

With the rising incidence of lung cancer and the anticipated implementation of lung cancer screening programs, the need for minimal invasive diagnostic procedures for small pulmonary nodules (PN) will increase. Cone-beam CT guided navigation bronchoscopy (CBCT-NB) is a novel diagnostic technique which utilizes CBCT to navigate towards and accurately sample small peripheral PN. CT guided transthoracic biopsy (TTNB) is currently the most widely available method of minimal invasive biopsy. It has high diagnostic accuracy, but also high complication rates (∼25%).

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