Abstract
This chapter describes environmental chemicals that cause cancer and genetic birth defects. Damage to DNA appears to be the cause of most cancer and genetic birth defects and may contribute to aging and heart disease as well. A major part of this DNA damage is caused by environmental chemicals, both natural and man-made. Many more chemicals will be added to the current list of human carcinogens and mutagens. A major area of public health can be prevented by: identifying environmental mutagens/ carcinogens, making a rough estimate of human risk based on the potency and amount of human exposure, and minimizing human exposure to the more dangerous of these agents. Thus, it appears likely that potency in a battery of short-term tests (many good ones have now been developed) may be able to be used as an aid in human risk assessment.
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