Abstract
A study was conducted on 400 goats in Luna Export Abattoir originated from district area of Borena Range land (that is Yabello and Negella) from November, 2008 to April, 2009 to estimate the prevalence of caseous lymphadenitis (CLA) in goats. Detail post mortem examination and bacteriology were applied to undertake this study. On the bases of post mortem and bacteriological results, the prevalence of caseous lymphadenitis was 15% (60/400), out of which 42 (70%), 13 (21.7%) and 5 (8.3%) were cutaneous form, visceral form and generalized form, respectively. There is statistical significance difference (P < 0.05) among the three age groups. The study revealed that as age increases the prevalence also increases. Statistical significant difference was also recorded between goats having poor and good body condition score (P < 0.05). Moreover, goats with poor body condition score seem to be more infected (24.7%) than those goats with good body condition (12.5%). In conclusion, this study has indicated the occurrence of CLA in high frequency in goats of Borena range land. Therefore, further extensive research should be conducted over all the country to determine prevalence and economic significance of the disease. Key words: Goats, Borena range land, Luna Export Abattoir, caseous lymphadenitis, post mortem examination, bacteriology, prevalence.  
Highlights
Caseous lymphadenitis (CLA) is a chronic, recurring and highly contagious bacterial infection caused by Corynbacterium pseudotuberculosis which can manifest itself as cutaneous or visceral disease of sheep and goat
A total of 400 goats were examined out of which, 60 (15%) suspicious CLA lesions were detected at post mortem examination
Prevalence of CLA recorded in this study was based on post mortem examination and bacteriology
Summary
Caseous lymphadenitis (CLA) is a chronic, recurring and highly contagious bacterial infection caused by Corynbacterium pseudotuberculosis which can manifest itself as cutaneous or visceral disease of sheep and goat.Corynbacterium pseudotuberculosis (C.pseudotuberculosis) produces an exotoxin, phosphlipaseD, which is leukotoxic and damages endothelial cells, propagating the spread of the organisms from the site of infection to the regional lymph nodes and visceral organs/structures. Caseous lymphadenitis (CLA) is a chronic, recurring and highly contagious bacterial infection caused by Corynbacterium pseudotuberculosis which can manifest itself as cutaneous or visceral disease of sheep and goat. D, which is leukotoxic and damages endothelial cells, propagating the spread of the organisms from the site of infection to the regional lymph nodes and visceral organs/. The cell wall of the bacterium is characterized by a high lipid content helping it to resist destruction by phagocytes and allowing for continued chronic infection (Nicastro, 2004).CLA is an endemic infection in regions with large sheep and goats’ population (East, 1998). The bacterium is spread when the infected lymph nodes of a diseased animal rupture and drain, infecting naive animals that come in contact with the purulent infectious exudates. The bacteria can survive over 24 h in dips and for months in moist dark conditions, such as a shearing shed (Augustine and Renshaw, 1986)
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