Abstract
Objective: The aim of the present study is to evaluate the value of inflammatory parameters and indices of complete blood count (CBC) and C-reactive protein (CRP) in predicting negative laparotomies and severity of acute appendicitis in adults.
 Material and Methods: A total of 1389 patients who had undergone appendectomy between January 2015 and November 2020 were enrolled in this observational and cross-sectional study. Age, gender, preoperative CRP values, inflammatory parameters of CBC and the pathologic diagnosis were recorded.
 Multivariate analysis and logistic regression analysis were performed.
 Results: In multivariate model white blood cell (WBC), platelet count (PLT), mean platelet volume (MPV), absolute neutrophil and lymphocyte counts, neutrophil percentage (NEU%), lymphocyte percentage (LYM%), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio and CRP-to-lymphocyte
 ratio (CLR) were significant discriminators of negative laparotomy (p
Published Version
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