Abstract
Endothelial dysfunction is an early marker for the development and progression of cardiovascular diseases. Scientific studies in recent years have shown the necessity to study the endothelial function in different groups of patients in clinical practice. This article is focused on the possibilities and perspectives for clinical use of laboratory and instrumental methods for the study of endothelial function. One of the factors causing the development of vascular disease in men is testosterone deficiency. The review highlights the most important mechanisms of action of sex hormones on the vascular endothelium and its function in men. The data about the effects of hormone replacement therapy with testosterone on endothelial function in patients with late onset hypogonadism were critically analyzed.
Highlights
Scientific studies in recent years have shown the necessity to study the endothelial function in different groups o f patients in clinical p ractice
This article is focused on the possibilities and perspectives for clinical use of lab o rato ry and instrum ental m ethods for the study of endothelial function
The data about the effects o f horm one replacem ent therapy with testosterone on endothelial function in patients with late onset hypogonadism were critically analyzed
Summary
Y ild iz O , Seyrek M , G ul H ., Un I ., Y ild ir im V , O zal E , Uzun M . K ang S .-M ., Jang Y ., K im J i.-Y ., C hung N ., Cho S .-Y ., Chae J.S., Lee J.-Ho. Effect of oral administration of testoster one on brachial arterial vasoreactivity in men with coronary a rte ry disease / / Am. J. Обзоры и лекции men before and after testosterone replacem ent therapy / / J.
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