Abstract
Recordings of rat neocortical and hippocampal EEG were taken during and following electrical stimulation of the medial septum. Low intensity stimulation which did not produce abnormal alterations of the hippocampal or cortical EEG resulted in behaviors such as hyperactivity, shaking, grooming, and yawning. As the stimulation intensity was increased, the effects on the electrical activity of both structures became more and more pronounced until prolonged, bilateral seizures followed by depression of the hippocampal electrical activity occurred. In all such instances, voracious eating was observed subsequently. The results indicate that care must be taken to distinguish the activation of neural mechanisms by artificial means through the use of such techniques as electrical and chemical stimulation, from that which occurs during or following pathological seizure activity.
Published Version
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