Abstract

Experiment 1 assessed the preference-aversion function of hamsters for water and 0.08, 0.15, 0.35, and 0.71 M NaCl solutions in the two-bottle test. Unlike rats, the hamsters did not show a strong preference for isotonic (0.15 M) saline, nor did they exhibit any preference for the other solutions. Experiment 2 examined the effects of hydrochlorothiazide on the hamsters' intake of 0.71 M NaCl solution. The results indicated that this diuretic agent did not cause the hamsters to increase their saline intake relative to the baseline level. Experiment 3 also indicated that a high (5 mg) dose of desoxycorticosterone acetate failed to produce sodium appetite in the hamsters. These results contrast with those found with rats.

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