Abstract

Synchronous field-potential bursts were induced in hippocampal slices with picrotoxin. Differential recording between intracellular and adjacent extracellular electrodes during paroxysmal depolarization shifts revealed rapid transmembrane depolarizations (TMDs), which were spike prepotentials generated by electrical field effects. These experiments demonstrate that endogenous electrical fields contribute to spike synchronization in the presence of convulsant drugs when excitatory chemical synapses are functional.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.