Abstract

Objective To compare the efficacy of video-assisted thoracoscopic surgery and open-thoracotomy in the treatment of lung cancer. Methods 77 patients with lung cancer were chose as study objects, all the patients were divided into two groups, 43 cases of video-assisted thoracoscopic surgery group (VATS) and 34 cases of open-thoracotomy group (OT) The operative time, blood loss, postoperative chest tube indwelling time and hospital stay and postoperative complication rate were compared.The VAS postoperative 1d, 3d, 5d after operation were calculated, and the serum CRP preoperative and postoperative 1d, postoperative 5d were detected. Results The operative time, postoperative chest tube indwelling time, hospital stay, the blood loss, the complication rate in VATS group and OT group were (134±52)min and (167±45)min, (2.50±0.30)d and (4.68±0.66)d, (4.77±0.54)d and (7.20±0.68)d, 103±26)mL and (248±43)mL, 11.63% and 38.24%, the differences were statistically significant (t=3.563, 3.725, 9.621, 3.402 and χ2=7.504, all P<0.05). The VAS postoperative 1d, 3d in VATS group and OT group were (6.22±0.82)score and (8.13±0.72)score, (4.46±0.48)score and (6.31±0.54)score, the differences were statistically significant, t=3.927, 3.742, all P<0.05; the serum CRP after 1d, 5d postoperative in VATS group and OT group were (38.32±9.59)μg/L and (58.43±10.62)μg/L, (17.71±5.42)μg/L and (36.65±8.25)μg/L, which were all higher than those of before surgery, but the serum CRP after 1d, 5d postoperative in VATS group were lower than those of OT group, the differences were statistically significant(t=5.541, 6.662, all P<0.05). Conclusion VATS lobectomy is a trauma, quicker recovery, less postoperative pain surgical methods, and can reduce postoperative acute phase reaction, which should be recommended as a treatment for lung cancer. Key words: Lung cancer; Lobectomy; Video-assisted thoracoscopic surgery; Open-thoracotomy

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