Abstract
Objective To evaluate the effects of the short-term intervention lifestyle intervention on metabolic measurements of community patients with impaired glucose regulation (IGR). Methods A total of 90 IGR participants were randomly assigned to the control group (n=45) or the intervention group (n=45). The subjects in the control group received routine diet and physical exercise advice once a month.The subjects in the intervention group received additional individualized diet counseling and circuit-type resistance training.Metabolic parameters were compared before or after the intervention between the two groups. Results In oral glucose tolerance test (OGTT), 2-h plasma glucose (PG) and homeostasis model of insulin resistance index (HOMA-IR) were significantly decreased in the intervention group at 3 months(F=13.47 or 82.25, both P<0.05). Body mass index (t=-2.44, P<0.05), systolic blood pressure (t=-3.39, P<0.05), diastolic blood pressure (t=-3.97, P<0.05), fasting plasma glucose (t=-3.89, P<0.05), 2-h PG (t=-7.22, P<0.05), total cholesterol (t=-2.72, P<0.05), low-density lipoprotein cholesterol (t=-2.74, P<0.05), and glycosylated hemoglobin A1C (t=-3.73, P<0.05) were significantly declined in the intervention group compared to the control group (all P<0.05). Conclusions Intensive lifestyle intervention can significantly improve the metabolic markers of IGR subjects and should be used to prevent type 2 diabetes. Key words: Life style; Early intervention(education); Community health services
Published Version
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