Effects of root canal therapy with different disinfectant drugs in patients with periodontal pulp combined disease

Abstract

Objective To investigate the clinical effects of root canal therapy with different disinfectants in patients with periodontal pulpal disease. Methods A total of 120 patients with periodontal pulp combined disease who underwent root canal treatment in General Hospital of Xishan Coal and Electricity Group from June 2017 to June 2018 were randomly divided into observation group and control group, with 60 cases in each group. The observation group was given tinidazole solution combined with minocycline hydrochloride, and the control group was given sodium hypochlorite solution combined with calcium hydroxide and chlorhexidine. The effects of the two groups were compared, and the changes of periodontal parameters in the two groups before and after treatment were analyzed. Results After 12 weeks of treatment, the total effective rate of the observation group (98.33%, 59/60) was higher than that of the control group (90.00%, 54/60). Before treatment, the clinical adhesion level (CAL), plaque index (PLI), bleeding index (BI), and depth of probing (PD) of the two groups were not significant different (P>0.05). After treatment, the CAL, PLI, BI, and PD values in the observation group were lower than those in the control group (P<0.05). Conclusions The combination of tinidazole solution and minocycline hydrochloride can improve the periodontal index of patients, enhance the antibacterial effect, effectively alleviate the patient’s symptoms, with can be recommend to clinical application. Key words: Periodontal pulpal disease; Root canal treatment; Disinfectant druy