Abstract
Objective To explore the effects of Res on the proliferation and apoptosis of human cervical cancer cell lines C33A, SiHa and HeLa. Methods Inhibition rates by different concentrations of Res were calculated using MTT method. Apoptosis rates and cell cycles were measured and examined by flow cytometry (FCM). Morphological configuration of apoptotic cells were observed under the fluorescence microscope. Results The growth of cancer cells was inhibited by Res of varied concentrations in a time- and dose-dependent manner ( P<0.01). The cells showed characteristic apoptosis morphologic changes under fluorescence microscope. Res exerted no effects on cell cycles. Conclusion Res inhibits the growth of cervical cell lines C33A, SiHa and HeLa by inducing cell apoptosis in a time- and dose-dependent manner.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
