Effects of Banxiaxiexin decoction on the intestinal microorganisms and enzyme activities in mice with spleendeficiency constipation

Yanfang Guo,Xianping Zhao,Huaying Hui,Lu He,Lan Shu,Zhoujin Tan

doi:10.7243/2050-120x-6-1

Abstract

Abstract The present study was carried out to investigate the impact of Banxiaxiexin Decoction on the intestinal microorganisms and enzyme activities in mice with spleen-deficiency constipation. 24 experimental mice were randomly

Highlights

Constipation is a common gastrointestinal complaint clinically [1,2], affecting an estimated 27% of global population [3]
From the ninth day to the fifteenth day, the mice of the model group and the Banxiaxiexin decoction (BXD) group and the ZZD group lasted the symptoms of spleen-deficiency constipation
After treated with ZZD and BXD for five days, the mice of the BXD group and the ZZD group restored their vitality in eyes and vigorous, the mice hair on back became thick and shiny, the diet and water drinking of the mice returned to normal, the particles of the feces became soft covering with mucus on the surface, the center of the feces was rich in water

Summary

Introduction

Constipation is a common gastrointestinal complaint clinically [1,2], affecting an estimated 27% of global population [3]. Each BXD and ZZD were made into water changes of the microbes and the enzyme activities in intestine decoction of appropriate concentration that equivalent to 1 of mice with spleen-deficiency constipation were significant g·mL-1 of crude drug concentration in the whole group. The activities of amylase and protease spleen-deficiency constipation and the normal group were reduced but the activities of xylanase and cellulase raised.

Results

Conclusion