Effect of Zhikang Capsule Assisted LEEP on Postoperative Recovery Speed and the Incidence of Complications of Patients with Cervical Intraepithelial Neoplasia

Abstract

Objective: To investigate the role of Zhikang capsule assisted loop electrosurgical excision procedure (LEEP) operation for intervening cervical intraepithelial neoplasia (CIN) on improving the recovery speed and reducing the incidence of complications. Methods: Altogether 91 CIN patients in our hospital were selected as the research participants. Patients treated with Zhikang capsule assisted LEEP operation were the research group (RG) (48 cases), and patients treated with LEEP operation were the control group (CG) (43 cases). The related indexes and incidence of postoperative complications between the CG and the RG were compared. Inflammatory reaction, immune function, psychological status score, total bleeding, hospital stay and quality of life were evaluated. Results: The drainage time, bleeding time and wound healing time in the RG were shorter than those in the CG (P<0.05). The incidence of complications in the RG was evidently lower than that in the CG (P=0.034). IL-4 in the RG was evidently lower than that in the CG (P<0.05), while IFN-γ and IL-2 were evidently higher than those in the CG (P<0.05). CD3+ and CD4+ in the RG were evidently higher than those in the CG (P<0.05), while CD8+ in the RG were evidently lower than those in the CG (P<0.05). After intervention, SDS and SAS scores in the RG were evidently lower than those in the CG (P<0.05). The total bleeding and hospital stay in the RG were less than those in the CG (P<0.05). The quality of life in the RG was better than that in the CG (P<0.05). Conclusion: Zhikang capsule assisted LEEP operation can effectively improve the recovery rate of patients and reduce the incidence of complications, which is worthy of clinical application.