Abstract
Objective: This study aimed to assess the clinical effectiveness of combining Jiaying Su (Ensure) and Rui Dai intestinal nutrition formula (TPF-D) in Intensive Care Unit (ICU) critically ill patients. Methods: A retrospective analysis was conducted on 79 patients admitted to the ICU ward between January 2022 and January 2024, who received nutritional support therapy. Patients were divided into a control group (receiving Jiaying Su alone) and an observation group (receiving combined Jiaying Su and Rui Dai). Nutritional indicators, blood glucose levels, immune function markers, inflammatory factors, occurrence of complications, and prognosis were compared between the two groups. Results: After 7 days of treatment, the observation group exhibited a greater increase in serum albumin (ALB) and prealbumin (PAB) levels compared to the control group (<i>P</i><0.05). Blood glucose levels, including fasting blood glucose (FBG) and postprandial 2-hour postprandial blood glucose, were significantly lower in the observation group than in the control group after treatment (<i>P</i><0.05). The observation group also demonstrated higher levels of immunoglobulin G, immunoglobulin A, and complement C3 compared to the control group (<i>P</i><0.05). Inflammatory markers, procalcitonin, and C-reactive protein levels were significantly reduced in both groups after treatment, with greater reductions observed in the observation group (<i>P</i><0.05). The incidence of enteral nutrition complications was lower in the observation group (<i>P</i><0.05), while the transfer from ICU to a general ward was higher (<i>P</i><0.05). Conclusion: The combined use of Jiaying Su and TPF-D demonstrated favorable clinical efficacy in ICU critically ill patients. Compared to Jiaying Su alone, the addition of Rui Dai promoted better nutritional recovery, regulated blood glucose levels, improved immune function, mitigated inflammatory responses, and enhanced patient prognosis.
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