Abstract
目的 比较晶体液和胶体液预负荷预防胸段硬膜外阻滞复合全麻诱导期低血压效应.方法ASA Ⅰ~Ⅱ级择期行上腹部手术患者90例,随机分为三组,每组30例.A、B和C三组分别以1000 ml复方乳酸钠注射液、500ml和1000 ml聚明胶肽溶液在40 min进行容量预负荷,在预负荷过程中,经T8~9行硬膜外穿刺置管,用1.6%利多卡因和0.2%丁卡因混合液进行硬膜外阻滞,预负荷结束后开始全麻诱导.结果硬膜外阻滞、全麻诱导后及气管插管后,A和B组血压显著低于C组,A、B和C组低血压的发生率分别为70%、57%和23%,C组显著低于A、B两组.结论胶体液容量预负荷预防胸段硬膜外阻滞复合全麻后低血压的效应优于等量的晶体液。
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