Abstract
Spermidine strongly stimulates the activity of DNA polymerase B but is ineffective in stimulating the activity of DNA polymerase A of rat brain. The extent to which spermidine stimulates the activity of DNA polymerase B depends on the DNA template used. Spermidine cannot replace Mg 2+ for DNA polymerase B activity. The stimulatory effect of spermidine does not seem to be due to removal of histone. The stimulation of DNA polymerase B activity by spermidine is much greater at lower concentrations of enzyme than at higher concentrations and so the enzyme concentration curve for DNA polymerase B is more linear in the presence of spermidine than in the absence.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
