Effect of Scaling and Root Surface Debridement on Lipid Profile in Type-2 Diabetes Patients with Chronic Periodontitis

Abstract

Objective: Periodontitis is the most common inflammatory conditions affecting the periodontal tissues and considered as one of the complications of type 2 diabetes mellitus. The study aimed to evaluate the effects of scaling and root surface debridement on clinical periodontal parameters and serum lipid profile levels in chronic periodontitis and type 2 diabetes patients.
 Methods: The study enrolled on 45 patients, 15 systemically healthy patients with chronic periodontitis, 15 well controlled (glycated hemoglobin <8%) and 15 poorly controlled (HbA1c ≥8%) type 2 diabetic patients with chronic periodontitis. Intra-oral clinical parameters (plaque index, gingival index, probing pocket depth, and clinical attachment loss) and blood samples were collected to test high density lipoprotein (HDL), low density lipoprotein (LDL), total cholesterol (TC) and triglyceride (TG) for all patients at baseline and after 30 days of periodontal therapy. One-way ANOVA used to compare between groups.
 Results: The study groups showed significant reduction in clinical periodontal parameters after 30 days of periodontal therapy (P < 0.000), while no significant differences were seen in serum lipid profile (P >0.05). Non-significant differences were also seen between the 3 groups in relation to clinical periodontal parameters and serum lipid profiles after periodontal therapy P > 0.05.
 Conclusions: Scaling and root surface debridement reduce clinical parameters of periodontitis in all study groups, however, no significant reduction of lipid profile were exhibited.