Abstract
Atherosclerosis is one of the most common cardiovascular diseases leading to high morbidity. The study of arterial dynamics using fluid–structure interaction (FSI) technique by taking into account the physiology of flow, the critical hemodynamic parameters can be determined which plays a crucial role in predictive medicine. Due to advances in the computational facilities, coupled field analysis such as FSI can facilitate understanding of the mechanics of stenosis progression and its early diagnosis. In this study a two-way FSI analysis is carried out using modified Navier–Stokes equations as the governing equations of blood flow for determining hemodynamic parameters. The arterial wall has been described at different linear elastic modulus and compared with hyperelastic Mooney–Rivlin model to evaluate the effect of different arterial stiffness on hemodynamics. The Mooney–Rivlin model predicts flow reduction with the severe backflow at arterial bifurcation resulting in decreased shear stress and oscillatory behavior. Furthermore, these findings may be used in understanding the advantages and disadvantages of using hyperelastic artery model in numerical simulations to better understand and predict the variable that causes cardiovascular diseases and as a diagnostic tool. In the present study, variation due to change in arterial wall properties such as linear elastic and Mooney Rivlin hyperelastic and its influence on hemodynamics are investigated.
Highlights
Atherosclerosis is a cardiovascular disease, which is the main cause of death in many advanced countries [1]
The results describe the important role in understanding the hemodynamic mechanism of stenosis
With reduced arterial stiffness, a linear elastic model is more suitable as the Mooney–Rivlin model resembles an artery of the healthy adult with an average elastic modulus of 0.9 MPa
Summary
Atherosclerosis is a cardiovascular disease, which is the main cause of death in many advanced countries [1] It is generally characterized by the accumulation of fatty particles, cholesterol, and other particles in the inner layer of the arterial wall. The formation of plaque is a localized phenomenon that generally occurs at locations such as bifurcations and curvatures observed in carotid arteries [3, 4]. These highly vulnerable sites are conditioned by hemodynamic parameters such as low wall shear stress (WSS), oscillatory flow, or Technical Editor: Monica Carvalho.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
