Abstract
Objective To discuss the effect of fentanyl application on fentanyl-propofol anesthesia recovery before skinning suture.Methods Thirty cases of thyroid gland adenoma excision were divided into F1,F2 and N groups,1 or 2 μg/kg fentanyl were given before skinning suture in F1or F2 group,N group as control group.The degree of pain and sedation were assessed,recovery time of breathing,consciousness recovery,extubation time and the adverse events were recorded,MAP and HR were continuing monitored.Results Compared with N group,score of VAS grade in F1 and F2 groups were significantly reduced (P ＜ 0.01);Score of Ratings Ramsay in F1 and F2 group were higher than in N group (P ＜ 0.01) ,and increased more significantly in F2 group (P ＜ 0.05).Compared with F1 and N group,recovery time of breathing,consciousness recovery and extubated time were extended in F2 group(P ＜ 0.01).During recovery,MAP and HR were gradually increased in N group,and remained relatively stable in F1 and F2 groups.Conclusion Before skinning suture of thyroid gland adenoma excision,application of 1 μg/kg fentanyl could reduce pain response of remifentanyl discontinuation,but not significantly delay recovery of consciousness and extubated time. Key words: Fentanyl; Remifentanil; Propofol; Postoperative pain
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